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Theoretical concepts from polymer and physical chemistry regarding the behaviour of multivalent molecules provide a mechanistic framework that can explain a wide range of cellular behaviours.
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Electronic address: [email protected]. PMID: 27374333 PMCID: PMC4967043 DOI: 10.1016/j.cell.2016.06.010 Abstract Cellular bodies such as P bodies and PML nuclear bodies (PML NBs) appear to be phase-separated liquids organized by multivalent interactions among proteins and RNA molecules.
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Cell, Volume 166 Supplemental Information Compositional Control of Phase-Separated Cellular Bodies Salman F. Banani, Allyson M. Rice, William B. Peeples, Yuan Lin, Saumya Jain, Roy Parker, and Michael K. Rosen. Supplemental Information Compositional Control of Phase Separated Cellular Bodies
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Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema. . 2020 May 14;181 (4):784-799.e19. doi: 10.1016/j.cell.2020.03.037. Philip Kitchen 1 , Mootaz M Salman 2 , Andrea M Halsey 3 , Charlotte Clarke-Bland 1 , Justin A MacDonald 4 , Hiroaki Ishida 5 , Hans J Vogel 6 , Sharif Almutiri 7 , Ann Logan 3 , Stefan Kreida.
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6,192 Followers, 2,592 Following, 31 Posts - See Instagram photos and videos from Salman Cell (@salman_cell_hassan)
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Salman F. Banani, Allyson M. Rice, William B. Peeples, Yuan Lin, Saumya Jain, Roy Parker, Michael K. Rosen Correspondence [email protected] In Brief What are the general principles that define the composition of phase-separated cellular bodies? Banani et al., 2016, Cell 166, 651-663 July 28, 2016 ª 2016 Elsevier Inc.
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Salman R. Punekar 1, Vamsidhar Velcheti 1, Benjamin G. Neel 1 &. Cancer Cell 15, 489-500 (2009). CAS PubMed PubMed Central Google Scholar.
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Dr. Salman Gilani is the Founder and Medical Director of Institute of Regenerative Medicine. He did his Medical Degree (MBBS) in Pakistan after which he went to USA where he did his specialization in Internal Medicine (M.D). There in the states, he got his Diplomate status through American Academy of Aesthetic Medicine.
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Tammera Sherrod
A multitude of cellular processes involve biomolecular condensates, which has led to the suggestion that diverse pathogenic mutations may dysregulate condensates. Although proof-of-concept studies have identified specific mutations that cause condensate dysregulation, the full scope of the pathological genetic variation that affects condensates.
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Go to: Abstract Biomolecular Condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes, but concentrate biomolecules including proteins and nucleic acids. They are involved in diverse processes, including RNA metabolism, ribosome biogenesis, the DNA damage response and signal transduction.
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Salman Fazal, MD, director of the cell transplantation program in the division of hematology & cellular therapy at the Allegheny Health Network, discusses the use cases for older matched sibling donors vs younger unrelated donors in stem cell transplants for patients with cancer.
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Introduction. Given the importance of cancer, research on timely diagnosis and effective treatment in cancer field is on the fast track [1, 2].Old different cancer therapies, such as radiotherapy and chemotherapy are both harmful to normal cell and many other side effects [3, 4].These limitations have led to the spread of studies on efficient therapeutic strategies specifically targeting.
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Indianapolis, IN Bio Huda Salman, MD, PhD, is the executive director of the Brown Center for Immunotherapy. Salman joined IU School of Medicine from Stony Brook University and Stony Brook Cancer Center, where she founded the hematological malignancies section as well as the Cancer Center Adolescence and Young Adult Program.
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All the different forms of life on our planet - including animals, plants, fungi and bacteria - tend to grow, multiply and expand. This happens through a process called cell division, where one cell becomes two; two cells become four; four cells become eight; and so on. Each dividing cell passes on the same set of genetic instructions to its two daughter cells in the form of DNA.
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Salman F Banani Hyun O Lee Anthony A Hyman Michael K Rosen 28225081 PMC7434221 10.1038/nrm.2017.7 Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack surrounding membranes but function to concentrate proteins and nucleic acids.